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Purecybin DMT is a psychedelic of the tryptamine class. It is found in a wide variety of plant species and in at least one toad species, the Sonora Desert toad. Furthermore, like its close relatives, DMT and bufotenine, it has been used as an entheogen in South America.
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Regardless, this DMT is a synthetic version of the original. To start, it lacks the intoxicating visuals of DMT and is four to six times stronger. On the contrary, this DMT is primarily recognized for its profound alteration of viewpoint and overwhelming sensations.
Formula: C13H18N2O
Molar mass: 218.298 g/mol
ChemSpider ID: 1766
ChEMBL Id: 7257
PubChem CID: 1832
IUPHAR ID: 145
There are two different types of DMT available in vape pen form:
N,N,DMT — this is the type of DMT most commonly found in plants. It’s the active ingredient in the traditional Shamanic brew known as ayahuasca.
5-MeO-DMT — this is the form of DMT found in the venom of the Bufo alvarius toad, as well as a few species of plants and fungi.
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Other forms of DMT share the same name but are considered to be distinct in terms of the effects they produce.
A good example of this is 4-AcO-DMT — similar to psilocybin and psilocin produced in magic mushrooms. The experience this compound produces is much mellower. It’s unlikely this compound will inject you into the types of interdimensional experiences produced by N,N,DMT or 5-MeO-DMT. It also lasts substantially longer (8 hours rather than 30 minutes).
There’s also 2-α-DMT, 4-MeO-DMT, 5-Bromo-DMT, α,N-DMT, and others.
What You Should Know About DMT Vape.
The active ingredients in a DMT vape pen can be N,N,DMT or 5-MeO-DMT, depending on the formulation. The next step is to combine it with a typical vaporizer, the same kind that cannabis growers use.
Actually, any vape pen that uses a cartridge style can be used with DMT vape cartridges. You can find these pens stocked with nicotine, CBD, or THC cartridges. The old tank is unscrewed and replaced with a new one when it is empty.
Vape pens are engineered to gently heat the contents, ensuring they remain undamaged. In order for the DMT and its base agent, which is typically e-liquid, to become vapour, they are heated to a precise point. This allows them to be inhaled through the lungs. The active ingredients are usually heated to about 400 oF, or 204 oC, in vape pens.
While smoking DMT is another option, the high temperatures (above 900 °C or 1500 °F) render most of the DMT ineffective and create hazardous combustion residues.
Pharmacology
5-MEO-DMT is a methoxylated derivative of DMT. Also, based on studies in rats, its pharmacological activity is believed to be mainly through serotonin receptors. Specifically, it shows high affinity for the 5-HT2 and 5-HT1A subtypes. Furthermore, additional mechanisms of action, such as inhibition of monoamine reuptake, may also be involved.
Also, a 2019 European study with 42 volunteers showed that a single inhalation produced sustained enhancement of satisfaction with life and easing of anxiety, depression, and post-traumatic stress disorder (PTSD).
Though this DMT is a chemical derivative of DMT, Firstly, it’s 4 to 6 times stronger than DMT and has far fewer of the visual’s characteristic of DMT. Instead, this DMT is mostly known for its intense perspective shifts and sensory overload.
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Most DMT powder users vape or smoke it. The effects start within 30 seconds and peak at 1–15 minutes, lasting up to 30 minutes. The artificial Purecybin DMT threshold dose is 1-2 mg; the moderate-to-strong dose is 5–10 mg. The naturally derived threshold dose is 5–10 mg, and the moderate-to-strong level is 20–40 mg.
Swallowing increases doses but decreases accuracy. Other less common administration methods include sublingual and injection.
The effects are strong and often cause loss of coordination and control. Higher doses cause bright colours, moving environments, recursive patterns, and possibly “environmental biism.” There are few visual effects. Five-MeO-DMT lacks the visionary properties of DMT. Most describe it as a “perspective shift” with physical, emotional, and conceptual effects.
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The Purecybin DMT experience often emphasises tactile awareness, sometimes to the point of sensory overload. Feeling heavier may also occur. From fear to euphoria, intense emotions are common. Early on, anxiety or excitement may occur. A sense of oneness with the universe, or being outside of time and space while experiencing both, is also common.
Purecybin DMT patients also experience ego death. Time dilation, nausea, auditory hallucinations, and memory loss are other effects.
DMT has been available online in the USA for years. Our store started selling DMT vapes online in the USA. In the USA, you can buy DMT online safely and discreetly.
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What Are the Benefits of DMT Vape Pens?
Simple to use — Breakthrough experiences are available to virtually everybody. When used responsibly, this may offer a substantial capacity for healing.
Ability to control the dose — By regulating how many hits you take and the amount of time you hold the vapor in your lungs, you can control the intensity of effects with a reasonable degree of accuracy.
Less harsh on your throat and lungs than smoking — Let’s be clear, vaping DMT is going to be harsh, but it’s far less harsh than smoking DMT.
What Are the Negatives of DMT Vape Pens?
Potential for abuse — vape pens are very easy to use too often and can become habit-forming.
Expensive — DMT is expensive, so whether you’re using a vape or smoking it, the price will be fairly high.
Potential health risks — DMT requires high heat to vaporize and can be harsh on the throat and lungs.
Highly illegal — DMT is a controlled substance in the United States and many other countries worldwide.
What Types of DMT Vape Pens Are There?
DMT vape pens can be broken down according to two categories:
The type of vaporizer products (cartridges, disposable vape pens, refillable DMT e-liquid)
The type of DMT used as the active ingredient (N,N,DMT or 5-MeO-DMT)
Types of DMT Commonly Found in Vapes
The two main forms of DMT found in vaporizer format are N,N,DMT and 5-MeO-DMT.
While both are forms of DMT, the experiences they produce differ quite a bit. In general, 5-MeO-DMT is more “spiritual” in that it tends to make users feel connected with the universe. Users often experience out-of-body experiences.
N,N,DMT is similar, but has a stronger visual component with sharp fractals and constantly changing geometric patterns. N,N,DMT is also strongly spiritual, but not as likely to result in a “god encounter” type experience as 5-MeO-DMT.
There’s a lot of debate about what type of DMT is “better,” but the truth is that neither one is better than the other — both are profound and formidable psychedelics that demand respect. Both substances have a similar potential for healing, as well as harm (when used irresponsibly).
1. N,N,DMT Vape Pens
These pens are the most common form of DMT vape pen. This is the same active ingredient that’s found in ayahuasca, changa, and yopo.
This form of DMT is associated with profound psychedelic and mystical experiences, introspection, and deep realizations about the self and consciousness.
Many experts consider this type of DMT to be a little bit better for self-realization and introspection. From a spiritual sense, this molecule tends to correlate more with a “feminine” embodiment. It’s more nurturing and guiding than 5-MeO-DMT.
2. 5-MeO-DMT Vape Pens
This compound is virtually identical to N,N,DMT — with just a few extra atoms attached. This is the same active ingredient that’s found in the secretions of the Bufo toad. Traditionally, the venom from this toad is collected and either eaten or smoked.
Today, it’s more common to see shamans administering 5-MeO-DMT in the form of a vape pen instead. The experience is virtually indistinguishable between the toad venom and synthetic DMT from a vape.
From a spiritual perspective, 5-MeO-DMT has more of a “masculine” embodiment and tends to be a little bit “rougher” on the participant. It’s less nourishing and introspective than N,N,DMT — but offers stronger visuals in exchange.
How to Use a DMT Vape Pen
The whole point of a DMT vape is that it’s simple to use. Nevertheless, there are a few steps to follow to get the most efficient hit from you vape.
Step 1: Shake the Pen
Always give the pen a good shake before you use it. The DMT will tend to separate from the e-liquid base, so if you skip this step, you will either get a hit of pure DMT or pure e-liquid.
Step 2: Take one Long Inhale, and Exhale Completely
This does two things; it calms you down before the hit, which is going to help reduce the chances of having a challenging or anxious experience. Secondly, it prepares you to take a longer, deeper breath during the next step, ultimately making the DMT more efficient.
Step 3: Take a Deep Inhale
Don’t rush it — inhale the vapor from the device slowly. It’s going to be pretty harsh, so taking longer, slower breaths will cut back on some of this harshness. Once you’ve taken a full inhale, release the pen and take one more inhale to bring all the vapor into the lungs.
Step 4: Hold Your Breath for a Few Seconds Before Exhaling
The DMT will immediately start absorbing through your lungs. Keeping the vapor in the lungs for a few seconds before exhaling allows you to get more efficiency from the DMT you’re using. The longer you hold your breath, the stronger the hit will be.
Step 5: Repeat as Necessary
Depending on the potency of your pen, the amount of vapor you inhaled, and the time you held the vapor in your lungs, you may need to take a few hits to reach breakthrough levels.
For a standard 400 mg, 0.5 mL vape cartridge, you may need between 5 and 15 hits to reach this effect level.
If using a mesh pen or stronger vape cartridge, you may only need 1–3 hits to reach breakthrough levels, so don’t rush it.
How Strong Are DMT Vape Pens?
Few psychedelics compete in terms of the depth of psychedelic experience than a DMT vape pen. They’re comparable in strength to ayahuasca but have substantially higher celerity.
Celerity is a term that describes the speed at which the psychedelic state of consciousness appears and disappears again.
Think “acceleration.” The faster a psychedelic accelerates, the sooner the race is over.
DMT vape pens are like a drag car — capable of reaching top speed almost instantly. But this comes at a cost — drag cars burn through their fuel quickly.
Substances with low celerity, like ayahuasca, take longer to get up to speed (reach peak effects) but also last much longer (6–10 hours). Ayahuasca is like a rally car — it’s much slower off the line but has the efficiency and fuel capacity to run for several hours.
A single hit of a vape pen can inject the user into deep psychedelic states in a matter of just a few seconds. The effects usually reach peak experience by the 10-minute mark and quickly fade out from there.
Just as fast as the experience begins, it goes away again. The total experience from a DMT vape pen rarely lasts longer than 30 minutes in total.
Is DMT The Strongest Psychedelic?
Some might argue that DMT (especially 5-MeO-DMT) is the strongest psychedelic based on the depth it brings the psychedelic explorer. The states of consciousness this compound can bring you to are hard to get to with any other psychedelic compound.
While this may be true, technically speaking, DMT isn’t the most potent psychedelic. This title goes to LSD (lysergic acid diethylamide) and LSD derivatives. The standard dose of 5-MeO-DMT (inhaled) is about 40 or 50 mg. The standard psychoactive dose for LSD, AL-LAD, PRO-LAD, ETH-LAD 1P-LSD, or related LSD-derivatives is only about a tenth of a milligram (100 mcg).
This makes LSD roughly 500 times stronger than DMT.
But it isn’t quite that simple. The top-level of the experience is higher with DMT — meaning that even high doses of LSD won’t provide an experience as strong as the standard psychoactive dose of DMT, even if both substances were used at the same dose (something that is definitely not recommended).
Is Vaping DMT Safe?
There are a lot of concerns about the safety of using DMT vape pens. There’s a higher potential for abuse with these devices than with most other psychedelics. The short-term and long-term side effects of using vapes are still not well understood.
Additionally, vapes make it much easier to use DMT irresponsibly, which could pose a serious risk to the mental health of people who aren’t applying the right context and integration with their experiences.
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